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Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells

Age related macular degeneration (AMD) is one of the leading causes of blindness. Genetics, environmental insult, and age-related factors all play a key role in altering proteostasis, the homeostatic process regulating protein synthesis, degradation and processing. These factors also play a role in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Govindaraju, Viren Kumar, Bodas, Manish, Vij, Neeraj
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540403/
https://ncbi.nlm.nih.gov/pubmed/28767736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182420
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