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Blocking AMPK/ULK1-dependent autophagy promoted apoptosis and suppressed colon cancer growth

BACKGROUND: Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechanism is poorly understood. METHODS: Cell viability and apoptosis were detected by...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Liu, Jing, Long, Shuaiyu, Wang, Huanan, Liu, Nannan, Zhang, Chuchu, Zhang, Lingling, Zhang, Yingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911288/
https://ncbi.nlm.nih.gov/pubmed/31871431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1054-0
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