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Blocking AMPK/ULK1-dependent autophagy promoted apoptosis and suppressed colon cancer growth

BACKGROUND: Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechanism is poorly understood. METHODS: Cell viability and apoptosis were detected by...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Liu, Jing, Long, Shuaiyu, Wang, Huanan, Liu, Nannan, Zhang, Chuchu, Zhang, Lingling, Zhang, Yingjie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911288/
https://ncbi.nlm.nih.gov/pubmed/31871431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1054-0
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