Enterotoxins can support CAR T cells against solid tumors

Responses of solid tumors to chimeric antigen receptor (CAR) T cell therapy are often minimal. This is potentially due to a lack of sustained activation and proliferation of CAR T cells when encountering antigen in a profoundly immunosuppressive tumor microenvironment. In this study, we investigate...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: von Scheidt, Bianca, Wang, Minyu, Oliver, Amanda J., Chan, Jack D., Jana, Metta K., Ali, Aesha I., Clow, Fiona, Fraser, John D., Quinn, Kylie M., Darcy, Phillip K., Kershaw, Michael H., Slaney, Clare Y.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911243/
https://ncbi.nlm.nih.gov/pubmed/31767744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904618116
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