Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells

OBJECTIVES: Adoptive transfer of chimeric antigen receptor (CAR)‐modified T cells is a form of cancer immunotherapy that has achieved remarkable efficacy in patients with some haematological cancers. However, challenges remain in CAR T‐cell treatment of solid tumours because of tumour‐mediated immun...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Chan, Jack D, von Scheidt, Bianca, Zeng, Bijun, Oliver, Amanda J, Davey, Ashleigh S, Ali, Aesha I, Thomas, Ranjeny, Trapani, Joseph A, Darcy, Phillip K, Kershaw, Michael H, Dolcetti, Riccardo, Slaney, Clare Y
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374388/
https://ncbi.nlm.nih.gov/pubmed/32704371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1157
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