Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells

OBJECTIVES: Adoptive transfer of chimeric antigen receptor (CAR)‐modified T cells is a form of cancer immunotherapy that has achieved remarkable efficacy in patients with some haematological cancers. However, challenges remain in CAR T‐cell treatment of solid tumours because of tumour‐mediated immun...

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Bibliografske podrobnosti
izdano v:Clin Transl Immunology
Main Authors: Chan, Jack D, von Scheidt, Bianca, Zeng, Bijun, Oliver, Amanda J, Davey, Ashleigh S, Ali, Aesha I, Thomas, Ranjeny, Trapani, Joseph A, Darcy, Phillip K, Kershaw, Michael H, Dolcetti, Riccardo, Slaney, Clare Y
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374388/
https://ncbi.nlm.nih.gov/pubmed/32704371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1157
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