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Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
The RhoGTPases are characterized as membrane-associated molecular switches that cycle between active, GTP-bound and inactive, GDP-bound states. However, 90–95% of RhoGTPases are maintained in a soluble form by RhoGDI, which is generally viewed as a passive shuttle for inactive RhoGTPases. Our curren...
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| 出版年: | eLife |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6910828/ https://ncbi.nlm.nih.gov/pubmed/31647414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50471 |
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