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A Review of Perspectives on the Use of Randomization in Phase II Oncology Trials

Historically, phase II oncology trials assessed a treatment’s efficacy by examining its tumor response rate in a single-arm trial. Then, approximately 25 years ago, certain statistical and pharmacological considerations ignited a debate around whether randomized designs should be used instead. Here,...

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Podrobná bibliografie
Vydáno v:J Natl Cancer Inst
Hlavní autoři: Grayling, Michael J, Dimairo, Munyaradzi, Mander, Adrian P, Jaki, Thomas F
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910171/
https://ncbi.nlm.nih.gov/pubmed/31218346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz126
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