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A stochastically curtailed single-arm phase II trial design for binary outcomes

Phase II clinical trials are a critical aspect of the drug development process. With drug development costs ever increasing, novel designs that can improve the efficiency of phase II trials are extremely valuable. Phase II clinical trials for cancer treatments often measure a binary outcome. The fin...

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Detalhes bibliográficos
Publicado no:J Biopharm Stat
Main Authors: Law, Martin, Grayling, Michael J., Mander, Adrian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614398/
https://ncbi.nlm.nih.gov/pubmed/35077268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2021.2009498
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