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A stochastically curtailed single-arm phase II trial design for binary outcomes

Phase II clinical trials are a critical aspect of the drug development process. With drug development costs ever increasing, novel designs that can improve the efficiency of phase II trials are extremely valuable. Phase II clinical trials for cancer treatments often measure a binary outcome. The fin...

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Publicat a:J Biopharm Stat
Autors principals: Law, Martin, Grayling, Michael J., Mander, Adrian P.
Format: Artigo
Idioma:Inglês
Publicat: 2022
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614398/
https://ncbi.nlm.nih.gov/pubmed/35077268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2021.2009498
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