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A stochastically curtailed single-arm phase II trial design for binary outcomes

Phase II clinical trials are a critical aspect of the drug development process. With drug development costs ever increasing, novel designs that can improve the efficiency of phase II trials are extremely valuable. Phase II clinical trials for cancer treatments often measure a binary outcome. The fin...

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Pubblicato in:J Biopharm Stat
Autori principali: Law, Martin, Grayling, Michael J., Mander, Adrian P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2022
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614398/
https://ncbi.nlm.nih.gov/pubmed/35077268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2021.2009498
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