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Intramuscular Allopregnanolone and Ganaxolone in a Mouse Model of Treatment Resistant Status Epilepticus
Allopregnanolone (5α-pregnan-3α-ol-20-one) and its synthetic 3β-methyl analog ganaxolone are positive allosteric modulators of synaptic and extrasynaptic GABA(A) receptors that exhibit antiseizure activity in diverse animal seizure models, including models of status epilepticus (SE). The two neuroac...
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| Publicado no: | Epilepsia |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6910080/ https://ncbi.nlm.nih.gov/pubmed/29453777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13999 |
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