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First‐in‐man allopregnanolone use in super‐refractory status epilepticus
Super‐refractory status epilepticus (SRSE) is associated with high morbidity and mortality. Treatment of SRSE is complicated by progressive cortical hyperexcitability believed to result in part from synaptic GABA receptor internalization and desensitization. Allopregnanolone, a neurosteroid that pos...
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| Veröffentlicht in: | Ann Clin Transl Neurol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454395/ https://ncbi.nlm.nih.gov/pubmed/28589168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.408 |
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