Fenretinide-induced Apoptosis of Acute Myeloid Leukemia Cells via NR4A1 Translocation into Mitochondria and Bcl-2 Transformation

OBJECTIVE: Fenretinide is reported to induce NR4A1-associated apoptosis in several types of cancer cells. However, it remains unclear about its specific role and the underlying mechanism in acute myeloid leukemia (AML). Therefore, this study aimed to explore the role and mechanism of fenretinide-ind...

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Bibliografski detalji
Izdano u:J Cancer
Glavni autori: Xiong, Jie, Kuang, Xingyi, Lu, Tingting, Liu, Xu, Cheng, Bingqing, Wang, Weili, Wei, Danna, Li, Xinyao, Zhang, Zhaoyuan, Fang, Qin, Wu, Depei, Wang, Jishi
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2019
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909957/
https://ncbi.nlm.nih.gov/pubmed/31839811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.32167
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