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Clonal expansion of bone marrow CD8(+) T cells in acute myeloid leukemia patients at new diagnosis and after chemotherapy

CD8(+) T cells are crucial adaptive immune effectors and express receptors (T cell receptors, TCRs) that specifically recognize and eradicate tumor cells. The diversity of the TCR repertoire is generated by specialized genetic diversification mechanisms, which lead to an extremely variable TCR reper...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Feng, Zhongxin, Fang, Qin, Kuang, Xingyi, Liu, Xin, Chen, Ying, Ma, Dan, Wang, Jishi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716150/
https://ncbi.nlm.nih.gov/pubmed/33294280
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