4SC-202 induces apoptosis in myelodysplastic syndromes and the underlying mechanism

Epigenetic modifications play crucial roles in regulating the self-renewal and differentiation of hematopoiesis. 4SC-202, a novel inhibitor of histone lysine-specific demethylase 1 (LSD1) and class I histone deacetylases (HDACs), is a potential therapeutic agent to treat myelodysplastic syndrome (MD...

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Detaylı Bibliyografya
Yayımlandı:Am J Transl Res
Asıl Yazarlar: Wang, Weili, Zhang, Zhaoyuan, Kuang, Xingyi, Ma, Dan, Xiong, Jie, Lu, Tingting, Zhang, Yaming, Yu, Kunling, Zhang, Siyu, Wang, Jishi, Fang, Qin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2020
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344078/
https://ncbi.nlm.nih.gov/pubmed/32655823
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