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Atroposelective Synthesis of Biaryl Diamines and Amino Alcohols via Chiral Phosphoric Acid Catalyzed para-Aminations of Anilines and Phenols

A versatile method for atroposelective synthesis of chiral biaryl diamines and amino alcohols has been developed via para-amination of anilines and phenols with azodicarboxylates enabled by chiral phosphoric acid catalysis. Meanwhile, highly efficient kinetic resolution of the racemic biaryl aniline...

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Vydáno v:iScience
Hlavní autoři: Wang, Donglei, Liu, Wei, Tang, Mengyao, Yu, Na, Yang, Xiaoyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909093/
https://ncbi.nlm.nih.gov/pubmed/31785557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.11.024
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