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Steric Modulation of Chiral Biaryl Diamines via Pd-Catalyzed Directed C–H Arylation

[Image: see text] Palladium-catalyzed directed arylation of 2,2′-diacetamidobiaryls with aryl iodides provides efficient access to chiral ortho-substituted biaryl diamines. Aryl iodides with para- and meta-substituents are tolerated. Deprotection of the acetyl groups under basic conditions furnishes...

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Detalhes bibliográficos
Main Authors: Scarborough, Christopher C., McDonald, Richard I., Hartmann, Caroline, Sazama, Graham T., Bergant, Ana, Stahl, Shannon S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726659/
https://ncbi.nlm.nih.gov/pubmed/19219972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo802632v
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