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Steric Modulation of Chiral Biaryl Diamines via Pd-Catalyzed Directed C–H Arylation
[Image: see text] Palladium-catalyzed directed arylation of 2,2′-diacetamidobiaryls with aryl iodides provides efficient access to chiral ortho-substituted biaryl diamines. Aryl iodides with para- and meta-substituents are tolerated. Deprotection of the acetyl groups under basic conditions furnishes...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726659/ https://ncbi.nlm.nih.gov/pubmed/19219972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo802632v |
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