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Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

The importance of axial chirality in enantioselective synthesis has been widely recognized for decades. The practical access to certain structures such as biaryl amino phenols known as NOBINs in enantiopure form, however, still remains a challenge. In drug delivery, the incorporation of axially chir...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Lu, Shenci, Ng, Shawn Voon Hwee, Lovato, Kaitlyn, Ong, Jun-Yang, Poh, Si Bei, Ng, Xiao Qian, Kürti, László, Zhao, Yu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624369/
https://ncbi.nlm.nih.gov/pubmed/31296858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10940-4
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