5-Aminolevulinate Synthase Catalysis: The Catcher in Heme Biosynthesis

5-Aminolevulinate (ALA) synthase (ALAS), a homodimeric pyridoxal-5’-phosphate (PLP)-dependent enzyme, catalyzes the first step of heme biosynthesis in metazoa, fungi and α-proteobacteria. In this review, we focus on the advances made in unraveling the mechanism of the ALAS-catalyzed reaction during...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Genet Metab
Asıl Yazarlar: Stojanovski, Bosko M., Hunter, Gregory A., Na, Insung, Uversky, Vladimir N., Jiang, Rays H. Y., Ferreira, Gloria C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908770/
https://ncbi.nlm.nih.gov/pubmed/31345668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2019.06.003
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