The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.

BP180, also termed collagen XVII, is a hemidesmosomal transmembrane glycoprotein expressed in basal keratinocytes, and functions as a cell-matrix adhesion molecule in the dermal-epidermal junction of the skin. Its function other than cell-matrix adhesion remains unclear. We generated a mouse strain...

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Veröffentlicht in:Oncogene
Hauptverfasser: Hwang, Bin-Jin, Zhang, Yang, Brozowski, Jaime M, Liu, Zhen, Burette, Susan, Lough, Kendall, Smith, Christof C, Shan, Yue, Chen, Jinbo, Li, Ning, Williams, Scott, Su, Maureen, Googe, Paul, Thomas, Nancy E., Liu, Zhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908749/
https://ncbi.nlm.nih.gov/pubmed/31435021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0961-9
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