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Collagen XVII (BP180) Modulates Keratinocyte Expression of the Proinflammatory Chemokine, IL-8

Collagen XVII (COL17), a transmembrane protein expressed in epidermal keratinocytes (EK), is targeted by pathogenic autoantibodies in bullous pemphigoid. Treatment of EK with anti-COL17 autoantibodies triggers the production of proinflammatory cytokines. In this paper we test the hypothesis that COL...

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Detalhes bibliográficos
Main Authors: Van den Bergh, Françoise, Eliason, Steven L., Burmeister, Brian T., Giudice, George J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395233/
https://ncbi.nlm.nih.gov/pubmed/22775995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0625.2012.01529.x
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