Chargement en cours...
The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension
Dysregulated bone morphogenetic protein (BMP) signaling in endothelial cells (ECs) is implicated in vascular diseases such as pulmonary arterial hypertension (PAH). Here, we showed that the transcription factor ATOH8 was a direct target of SMAD1/5 and was induced in a manner dependent on BMP but ind...
Enregistré dans:
| Publié dans: | Sci Signal |
|---|---|
| Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6908447/ https://ncbi.nlm.nih.gov/pubmed/31719172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aay4430 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|