טוען...
The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension
Dysregulated bone morphogenetic protein (BMP) signaling in endothelial cells (ECs) is implicated in vascular diseases such as pulmonary arterial hypertension (PAH). Here, we showed that the transcription factor ATOH8 was a direct target of SMAD1/5 and was induced in a manner dependent on BMP but ind...
שמור ב:
| הוצא לאור ב: | Sci Signal |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6908447/ https://ncbi.nlm.nih.gov/pubmed/31719172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aay4430 |
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