Search-and-replace genome editing without double-strand breaks or donor DNA

Most genetic variants that contribute to disease(1) are challenging to correct efficiently and without excess byproducts(2–5). Here we describe prime editing, a versatile and precise genome editing method that directly writes new genetic information into a specified DNA site using a catalytically im...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nature
Autors principals: Anzalone, Andrew V., Randolph, Peyton B., Davis, Jessie R., Sousa, Alexander A., Koblan, Luke W., Levy, Jonathan M., Chen, Peter J., Wilson, Christopher, Newby, Gregory A., Raguram, Aditya, Liu, David R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907074/
https://ncbi.nlm.nih.gov/pubmed/31634902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1711-4
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars