A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing

G-protein coupled receptors (GPCRs) are central to how mammalian cells sense and respond to chemicals. Mammalian olfactory receptors (ORs), the largest family of GPCRs, mediate the sense of smell through activation by small molecules, though for most bonafide ligands have not been identified. Here,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Syst
Prif Awduron: Jones, Eric M., Jajoo, Rishi, Cancilla, Daniel, Lubock, Nathan B., Wang, Jeff, Satyadi, Megan, Chong, Rockie, de March, Claire, Bloom, Joshua S., Matsunami, Hiroaki, Kosuri, Sriram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907015/
https://ncbi.nlm.nih.gov/pubmed/30904378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.02.009
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg