A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing

G-protein coupled receptors (GPCRs) are central to how mammalian cells sense and respond to chemicals. Mammalian olfactory receptors (ORs), the largest family of GPCRs, mediate the sense of smell through activation by small molecules, though for most bonafide ligands have not been identified. Here,...

詳細記述

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書誌詳細
出版年:Cell Syst
主要な著者: Jones, Eric M., Jajoo, Rishi, Cancilla, Daniel, Lubock, Nathan B., Wang, Jeff, Satyadi, Megan, Chong, Rockie, de March, Claire, Bloom, Joshua S., Matsunami, Hiroaki, Kosuri, Sriram
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907015/
https://ncbi.nlm.nih.gov/pubmed/30904378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.02.009
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