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Tension in fibrils suppresses their enzymatic degradation – a molecular mechanism for ‘Use it or Lose it’
Tissue homeostasis depends on a balance of synthesis and degradation of constituent proteins, with use of a given protein potentially regulating its turnover. Extracellular matrix (ECM) is predominantly composed of fibrillar collagens that exhibit tension-sensitive degradation, which we review here...
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| Publicado no: | Matrix Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6906264/ https://ncbi.nlm.nih.gov/pubmed/31201857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2019.06.001 |
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