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The Catalytic M-center of Copper Monooxygenases probed by Rational Design. Effects of Selenomethionine and Histidine Substitution on Structure and Reactivity.
The M-centers of the mononuclear monooxygenases peptidylglycine monooxygenase (PHM) and dopamine β-monooxygenase (DBM) bind and activate dioxygen on route to substrate hydroxylation. Recently we reported the rational design of a protein-based model wherein the CusF metallochaperone was repurposed vi...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6905645/ https://ncbi.nlm.nih.gov/pubmed/31626532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00823 |
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