A Mechanosensitive Channel Governs Lipid Flippase-Mediated Echinocandin Resistance in Cryptococcus neoformans

Echinocandins show fungicidal activity against common invasive mycoses but are ineffective against cryptococcosis. The underlying mechanism for echinocandin resistance in Cryptococcus neoformans remains poorly understood but has been shown to involve Cdc50, the regulatory subunit of lipid flippase....

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Foilsithe in:mBio
Main Authors: Cao, Chengjun, Wang, Yina, Husain, Seema, Soteropoulos, Patricia, Xue, Chaoyang
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904872/
https://ncbi.nlm.nih.gov/pubmed/31822582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01952-19
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