The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1

There is an urgent need for the development of potent vaccination regimens that are able to induce specific T and B cell responses against human immunodeficiency virus type 1 (HIV-1). Here, we describe the generation and characterization of a fusion antigen comprised of the HIV-1 envelope GP120 glyc...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Raman, Suresh C., Mejías-Pérez, Ernesto, Gomez, Carmen E., García-Arriaza, Juan, Perdiguero, Beatriz, Vijayan, Aneesh, Pérez-Ruiz, Mar, Cuervo, Ana, Santiago, César, Sorzano, Carlos Oscar S., Sánchez-Corzo, Cristina, Moog, Christiane, Burger, Judith A., Schorcht, Anna, Sanders, Rogier W., Carrascosa, José L., Esteban, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904342/
https://ncbi.nlm.nih.gov/pubmed/31867001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02793
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