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Clusterin accumulates in synapses in Alzheimer’s disease and is increased in apolipoprotein E4 carriers
One of the major challenges in developing effective therapeutic strategies for Alzheimer’s disease is understanding how genetic risk factors contribute to neurodegeneration. The apolipoprotein epsilon 4 isoform (APOE4) and variants in the Clusterin (CLU) gene (also known as apolipoprotein J) are ass...
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| Publicado no: | Brain Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6904249/ https://ncbi.nlm.nih.gov/pubmed/31853523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcz003 |
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