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Cell size pleomorphism drives aberrant clone dispersal in proliferating epithelia

As epithelial tissues develop, groups of cells related by descent tend to associate in clonal populations rather than dispersing within the cell layer. While frequently assumed to be a result of differential adhesion, precise mechanisms controlling clonal cohesiveness remain unknown. Here we employ...

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Publicat a:Dev Cell
Autors principals: Ramanathan, Subramanian P., Krajnc, Matej, Gibson, Matthew C.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903429/
https://ncbi.nlm.nih.gov/pubmed/31495693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.08.005
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