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Cell size pleomorphism drives aberrant clone dispersal in proliferating epithelia

As epithelial tissues develop, groups of cells related by descent tend to associate in clonal populations rather than dispersing within the cell layer. While frequently assumed to be a result of differential adhesion, precise mechanisms controlling clonal cohesiveness remain unknown. Here we employ...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Ramanathan, Subramanian P., Krajnc, Matej, Gibson, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903429/
https://ncbi.nlm.nih.gov/pubmed/31495693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.08.005
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