Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

Bone sarcomas such as osteosarcoma and chondrosarcoma are frequently refractory to conventional chemotherapy and radiotherapy that exhibit poor prognosis. The Wnt signaling are evolutionarily conserved and implicated in cell proliferation and sarcomagenesis. However, the potential role of the Wnt si...

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Udgivet i:Oncotarget
Main Authors: Chen, Changbao, Zhao, Meng, Tian, Aixian, Zhang, Xiaolin, Yao, Zhi, Ma, Xinlong
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627329/
https://ncbi.nlm.nih.gov/pubmed/25999350
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