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Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

Bone sarcomas such as osteosarcoma and chondrosarcoma are frequently refractory to conventional chemotherapy and radiotherapy that exhibit poor prognosis. The Wnt signaling are evolutionarily conserved and implicated in cell proliferation and sarcomagenesis. However, the potential role of the Wnt si...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Chen, Changbao, Zhao, Meng, Tian, Aixian, Zhang, Xiaolin, Yao, Zhi, Ma, Xinlong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627329/
https://ncbi.nlm.nih.gov/pubmed/25999350
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