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Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

Bone sarcomas such as osteosarcoma and chondrosarcoma are frequently refractory to conventional chemotherapy and radiotherapy that exhibit poor prognosis. The Wnt signaling are evolutionarily conserved and implicated in cell proliferation and sarcomagenesis. However, the potential role of the Wnt si...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Changbao, Zhao, Meng, Tian, Aixian, Zhang, Xiaolin, Yao, Zhi, Ma, Xinlong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627329/
https://ncbi.nlm.nih.gov/pubmed/25999350
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