Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

Bone sarcomas such as osteosarcoma and chondrosarcoma are frequently refractory to conventional chemotherapy and radiotherapy that exhibit poor prognosis. The Wnt signaling are evolutionarily conserved and implicated in cell proliferation and sarcomagenesis. However, the potential role of the Wnt si...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Chen, Changbao, Zhao, Meng, Tian, Aixian, Zhang, Xiaolin, Yao, Zhi, Ma, Xinlong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627329/
https://ncbi.nlm.nih.gov/pubmed/25999350
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