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Oncolytic viruses engineered to enforce leptin expression reprogram tumor-infiltrating T cell metabolism and promote tumor clearance

Immunotherapy can reinvigorate dormant responses to cancer, but response rates remain low. Oncolytic viruses, which replicate in cancer cells, induce tumor lysis and immune priming, but their immune consequences are unclear. We profiled the infiltrate of aggressive melanomas induced by oncolytic Vac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Immunity
मुख्य लेखकों: Rivadeneira, Dayana B., DePeaux, Kristin, Wang, Yiyang, Kulkarni, Aditi, Tabib, Tracy, Menk, Ashley V., Sampath, Padmavathi, Lafyatis, Robert, Ferris, Robert L., Sarkar, Saumendra N., Thorne, Stephen H., Delgoffe, Greg M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903394/
https://ncbi.nlm.nih.gov/pubmed/31471106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.07.003
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