Mitophagy protects against statin-mediated skeletal muscle toxicity

The deleterious effects of statins on skeletal muscle are well known, but the mechanism associated with these effects remains unresolved. Statins are associated with mitochondrial damage, which may contribute to muscle myopathy. Here we demonstrate that simvastatin induces mitophagy in skeletal musc...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Ramesh, Mridula, Campos, Juliane C., Lee, Pamela, Song, Yang, Hernandez, Genaro, Sin, Jon, Tucker, Kyle C., Saadaeijahromi, Hannaneh, Gurney, Michael, Ferreira, Julio C. B., Andres, Allen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902735/
https://ncbi.nlm.nih.gov/pubmed/31365836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900807RR
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi