TREM2 deficiency aggravates α-synuclein–induced neurodegeneration and neuroinflammation in Parkinson’s disease models

Variants in the gene encoding the triggering receptor expressed on myeloid cells 2 (TREM2) are known to increase the risk of developing Alzheimer disease and Parkinson’s disease (PD). However, the potential role of TREM2 effect on synucleinopathy has not been characterized. In this study, we investi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FASEB J
Main Authors: Guo, Ying, Wei, Xinbing, Yan, Hua, Qin, Yue, Yan, Shaoqi, Liu, Jia, Zhao, Yong, Jiang, Fan, Lou, Haiyan
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902667/
https://ncbi.nlm.nih.gov/pubmed/31370707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900992R
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