Mechanoregulation of p38 activity enhances endoplasmic reticulum stress–mediated inflammation by arterial endothelium

Endothelial up-regulation of VCAM-1 at susceptible sites in arteries modulates the recruitment efficiency of inflammatory monocytes that initiates atherosclerotic lesion formation. We reported that hydrodynamic shear stress (SS) mechanoregulates inflammation in human aortic endothelial cells through...

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Udgivet i:FASEB J
Main Authors: Bailey, Keith A., Moreno, Emily, Haj, Fawaz G., Simon, Scott I., Passerini, Anthony G.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902662/
https://ncbi.nlm.nih.gov/pubmed/31499005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900236R
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