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Mechanoregulation of p38 activity enhances endoplasmic reticulum stress–mediated inflammation by arterial endothelium

Endothelial up-regulation of VCAM-1 at susceptible sites in arteries modulates the recruitment efficiency of inflammatory monocytes that initiates atherosclerotic lesion formation. We reported that hydrodynamic shear stress (SS) mechanoregulates inflammation in human aortic endothelial cells through...

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發表在:FASEB J
Main Authors: Bailey, Keith A., Moreno, Emily, Haj, Fawaz G., Simon, Scott I., Passerini, Anthony G.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902662/
https://ncbi.nlm.nih.gov/pubmed/31499005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900236R
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