Moderate endoplasmic reticulum stress activates a PERK and p38-dependent apoptosis

The endoplasmic reticulum (ER) has the ability to signal organelle dysfunction via a complex signaling network known as the unfolded protein response (UPR). In this work, hamster fibroblast cells exhibiting moderate levels of ER stress were compared to those exhibiting severe ER stress. Inhibition o...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Lumley, Emily C., Osborn, Acadia R., Scott, Jessica E., Scholl, Amanda G., Mercado, Vicki, McMahan, Young T., Coffman, Zachary G., Brewster, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225058/
https://ncbi.nlm.nih.gov/pubmed/27761878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0740-2
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