Cdc7 kinase stimulates Aurora B kinase in M-phase

The conserved serine-threonine kinase, Cdc7, plays a crucial role in initiation of DNA replication by facilitating the assembly of an initiation complex. Cdc7 is expressed at a high level and exhibits significant kinase activity not only during S-phase but also during G2/M-phases. A conserved mitoti...

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Udgivet i:Sci Rep
Main Authors: Ito, Sayuri, Goto, Hidemasa, Kuniyasu, Kinue, Shindo, Mayumi, Yamada, Masayuki, Tanaka, Kozo, Toh, Gaik-Theng, Sawa, Masaaki, Inagaki, Masaki, Bartek, Jiri, Masai, Hisao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901529/
https://ncbi.nlm.nih.gov/pubmed/31819079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54738-2
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