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Regulation and roles of Cdc7 kinase under replication stress

Cdc7 (cell division cycle 7) kinase together with its activation subunit ASK (also known as Dbf4) play pivotal roles in DNA replication and contribute also to other aspects of DNA metabolism such as DNA repair and recombination. While the biological significance of Cdc7 is widely appreciated, the mo...

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Autores principales: Yamada, Masayuki, Masai, Hisao, Bartek, Jiri
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111749/
https://ncbi.nlm.nih.gov/pubmed/24841992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29251
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