Molecular Mechanism of Activation of Human Cdc7 Kinase: BIPARTITE INTERACTION WITH Dbf4/ACTIVATOR OF S PHASE KINASE (ASK) ACTIVATION SUBUNIT STIMULATES ATP BINDING AND SUBSTRATE RECOGNITION

Cdc7 is a serine/threonine kinase conserved from yeasts to human and is known to play a key role in the regulation of initiation at each replication origin. Its catalytic function is activated via association with the activation subunit Dbf4/activator of S phase kinase (ASK). It is known that two co...

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Detalhes bibliográficos
Main Authors: Kitamura, Ryo, Fukatsu, Rino, Kakusho, Naoko, Cho, Yong-Soon, Taniyama, Chika, Yamazaki, Satoshi, Toh, Gaik-theng, Yanagi, Kazuo, Arai, Naoko, Chang, Ho-Jin, Masai, Hisao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123071/
https://ncbi.nlm.nih.gov/pubmed/21536671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243311
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