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Mechanism of Cancer Cell Death Induced by Depletion of an Essential Replication Regulator
BACKGROUND: Depletion of replication factors often causes cell death in cancer cells. Depletion of Cdc7, a kinase essential for initiation of DNA replication, induces cancer cell death regardless of its p53 status, but the precise pathways of cell death induction have not been characterized. METHODO...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3344859/ https://ncbi.nlm.nih.gov/pubmed/22574151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036372 |
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