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Small Molecule Rescue and Glycosidic Conformational Analysis of the Twister Ribozyme

The number of self-cleaving ribozymes has increased sharply in recent years giving rise to elaborations of the four known ribozyme catalytic strategies α, β, γ, and δ. One such extension is utilized by the twister ribozyme, which is hypothesized to conduct δ, or general acid catalysis, via N3 of the...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Messina, Kyle J., Kierzek, Ryszard, Tracey, Matthew A., Bevilacqua, Philip C.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901379/
https://ncbi.nlm.nih.gov/pubmed/31742390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00742
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