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Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space
Small ribozymes such as Oryza sativa twister spontaneously cleave their own RNA when the ribozyme folds into its active conformation. The coupling between twister folding and self-cleavage has been difficult to study, however, because the active ribozyme rapidly converts to product. Here, we describ...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275738/ https://ncbi.nlm.nih.gov/pubmed/32430319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003425117 |
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