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Small Molecule Rescue and Glycosidic Conformational Analysis of the Twister Ribozyme
The number of self-cleaving ribozymes has increased sharply in recent years giving rise to elaborations of the four known ribozyme catalytic strategies α, β, γ, and δ. One such extension is utilized by the twister ribozyme, which is hypothesized to conduct δ, or general acid catalysis, via N3 of the...
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| Publié dans: | Biochemistry |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901379/ https://ncbi.nlm.nih.gov/pubmed/31742390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00742 |
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