Metabolite-sensing receptor Ffar2 regulates colonic group 3 innate lymphoid cells and gut immunity

Group 3 innate lymphoid cells (ILC3s) sense environmental signals that are critical for gut homeostasis and host defense. However, the metabolite-sensing G-protein-coupled receptors that regulate colonic ILC3s remain poorly understood. We found that colonic ILC3s expressed Ffar2, a microbial metabol...

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Gepubliceerd in:Immunity
Hoofdauteurs: Chun, Eunyoung, Lavoie, Sydney, Fonseca-Pereira, Diogo, Bae, Sena, Michaud, Monia, Hoveyda, Hamid R., Fraser, Graeme L., Gallini Comeau, Carey Ann, Glickman, Jonathan N., Fuller, Miles H., Layden, Brian T., Garrett, Wendy S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901086/
https://ncbi.nlm.nih.gov/pubmed/31628054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.09.014
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