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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

G protein-coupled receptors have been well described to contribute to the regulation of glucose-stimulated insulin secretion (GSIS). The short-chain fatty acid-sensing G protein-coupled receptor, free fatty acid receptor 2 (FFAR2), is expressed in pancreatic β-cells, and in rodents, its expression i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Priyadarshini, Medha, Villa, Stephanie R., Fuller, Miles, Wicksteed, Barton, Mackay, Charles R., Alquier, Thierry, Poitout, Vincent, Mancebo, Helena, Mirmira, Raghavendra G., Gilchrist, Annette, Layden, Brian T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484778/
https://ncbi.nlm.nih.gov/pubmed/26075576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1007
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