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The majority of A-to-I RNA editing is not required for mammalian homeostasis
BACKGROUND: Adenosine-to-inosine (A-to-I) RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I editing can change the protein coding potential of a transcript and alter RNA splicing, miRNA biology, RNA secondary structure...
Enregistré dans:
| Publié dans: | Genome Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900863/ https://ncbi.nlm.nih.gov/pubmed/31815657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1873-2 |
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