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What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs

Adenosine-to-inosine (A-to-I) editing is a post-transcriptional modification of RNA which changes its sequence, coding potential and secondary structure. Catalysed by the adenosine deaminase acting on RNA (ADAR) proteins, ADAR1 and ADAR2, A-to-I editing occurs at approximately 50 000–150 000 sites i...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Heraud-Farlow, Jacki E., Walkley, Carl R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574547/
https://ncbi.nlm.nih.gov/pubmed/32603639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200085
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